How about providing enough information to at least give someone a chance at helping you sort out this issue...
- What Operating system are you running? (Include Service pack #)
- What type of wireless service and devices are we talking about here? (Please include model revision for hardware used.)
- What sound card are you using and what version of the drivers are you running?
- What kind of speakers, and are they also wireless?
- How close are the speakers to the wireless device?
- Do you get any sound at all?
- Does the "interference" go away when you turn off the wireless device?
- Did installing a new piece of hardware make the speakers always produce a static noise and no normal sound at all?
This is just a start, but there are so many things that can cause interference in a case like this that it's going to take a lot of Q&A and some patience on your part to nail it down.
Could be something as simple as a conflicting IRQ.
PS: I don't really think this is the proper sub-forum for this topic.